Applying a Targeted Label-free Approach using LC-MS AMT Tags to Evaluate Changes in Protein Phosphorylation Following Phosphatase Inhibition

In order to identify phosphoproteins regulated by the phosphoprotein phosphatase (PPP) family of S/T phosphatases, we performed a large-scale characterization of changes in protein phosphorylation on extracts from HeLa cells treated with or without calyculin A, a potent PPP enzyme inhibitor. A label...

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Detalhes bibliográficos
Main Authors: Yang, Feng, Jaitly, Navdeep, Jayachandran, Hemalatha, Luo, Quanzhou, Monroe, Matthew E., Du, Xiuxia, Gritsenko, Marina A., Zhang, Rui, Anderson, David J., Purvine, Samuel O., Adkins, Joshua N., Moore, Ronald J., Ding, Shi-Jian, Mottaz, Heather M., Lipton, Mary S., Camp, David G., Udseth, Harold R., Smith, Richard D., Rossie, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516346/
https://ncbi.nlm.nih.gov/pubmed/17929957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr070068e
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