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Structural basis for induced formation of the inflammatory mediator prostaglandin E(2)
Prostaglandins (PG) are bioactive lipids produced from arachidonic acid via the action of cyclooxygenases and terminal PG synthases. Microsomal prostaglandin E synthase 1 (MPGES1) constitutes an inducible glutathione-dependent integral membrane protein that catalyzes the oxidoreduction of cyclooxyge...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516235/ https://ncbi.nlm.nih.gov/pubmed/18682561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802894105 |
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