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Structural basis for induced formation of the inflammatory mediator prostaglandin E(2)

Prostaglandins (PG) are bioactive lipids produced from arachidonic acid via the action of cyclooxygenases and terminal PG synthases. Microsomal prostaglandin E synthase 1 (MPGES1) constitutes an inducible glutathione-dependent integral membrane protein that catalyzes the oxidoreduction of cyclooxyge...

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Detalhes bibliográficos
Main Authors: Jegerschöld, Caroline, Pawelzik, Sven-Christian, Purhonen, Pasi, Bhakat, Priyaranjan, Gheorghe, Karina Roxana, Gyobu, Nobuhiko, Mitsuoka, Kaoru, Morgenstern, Ralf, Jakobsson, Per-Johan, Hebert, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516235/
https://ncbi.nlm.nih.gov/pubmed/18682561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802894105
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