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Ion permeation through a Cl(−)-selective channel designed from a CLC Cl(−)/H(+) exchanger
The CLC family of Cl(−)-transporting proteins includes both Cl(−) channels and Cl(−)/H(+) exchange transporters. CLC-ec1, a structurally known bacterial homolog of the transporter subclass, exchanges two Cl(−) ions per proton with strict, obligatory stoichiometry. Point mutations at two residues, Gl...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516207/ https://ncbi.nlm.nih.gov/pubmed/18678918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804503105 |
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