Human Betaine-Homocysteine Methyltransferase (BHMT) and BHMT2: Common Gene Sequence Variation and Functional Characterization

Betaine-homocysteine methyltransferase (BHMT) catalyzes the remethylation of homocysteine. BHMT2 encodes a protein 73% identical in amino acid sequence to BHMT, but the function of BHMT2 remains unclear. We set out to identify and functionally characterize common genetic variation in BHMT and BHMT2....

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Autors principals: Li, Fang, Feng, Qiping, Lee, Candace, Wang, Shuzhan, Pelleymounter, Linda L., Moon, Irene, Eckloff, Bruce W., Wieben, Eric D., Schaid, Daniel J., Yee, Vivien, Weinshilboum, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515933/
https://ncbi.nlm.nih.gov/pubmed/18457970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2008.03.013
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