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Implications of hedgehog signaling antagonists for cancer therapy

The hedgehog pathway, initially discovered by two laureates Drs. E. Wieschaus and C. Nusslein-Volhard in Drosophila, is a major regulator for cell differentiation, tissue polarity and cell proliferation. Studies from many laboratories including ours reveal activation of this pathway in most basal ce...

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Detalhes bibliográficos
Autor principal: Xie, Jingwu
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515624/
https://ncbi.nlm.nih.gov/pubmed/18604459
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