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Targeting hedgehog signaling in cancer: research and clinical developments
Since its first description in Drosophila by Drs Nusslein-Volhard and Wieschaus in 1980, hedgehog (Hh) signaling has been implicated in regulation of cell differentiation, proliferation, tissue polarity, stem cell maintenance, and carcinogenesis. The first link of Hh signaling to cancer was establis...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797650/ https://ncbi.nlm.nih.gov/pubmed/24143114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S34678 |
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