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Colchicine inhibits pressure-induced tumor cell implantation within surgical wounds and enhances tumor-free survival in mice

Iatrogenic tumor cell implantation within surgical wounds can compromise curative cancer surgery. Adhesion of cancer cells, in particular colon cancer cells, is stimulated by exposure to increased extracellular pressure through a cytoskeleton-dependent signaling mechanism requiring FAK, Src, Akt, an...

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Detalhes bibliográficos
Main Authors: Craig, David H., Owen, Cheri R., Conway, William C., Walsh, Mary F., Downey, Christina, Basson, Marc D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515382/
https://ncbi.nlm.nih.gov/pubmed/18704196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34279
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