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Synthesis of Functionalized Organotrifluoroborates via the 1,3-Dipolar Cycloaddition of Azides

We have successfully prepared potassium azidoalkyltrifluoroborates from the corresponding halogen compounds in 94–98% yields through a nucleophilic substitution reaction with NaN(3). In the presence of various alkynes and CuI as a catalyst, these azidotrifluoroborates easily formed 1,4-disubstituted...

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Detalhes bibliográficos
Main Authors: Molander, Gary A., Ham, Jungyeob
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515368/
https://ncbi.nlm.nih.gov/pubmed/16774252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol060826r
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