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RNA interference for CFTR attenuates lung fluid absorption at birth in rats

BACKGROUND: Small interfering RNA (siRNA) against αENaC (α-subunit of the epithelial Na channel) and CFTR (cystic fibrosis transmembrane conductance regulator) was used to explore ENaC and CTFR function in newborn rat lungs. METHODS: Twenty-four hours after trans-thoracic intrapulmonary (ttip) injec...

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Detalhes bibliográficos
Main Authors: Li, Tianbo, Koshy, Shyny, Folkesson, Hans G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515309/
https://ncbi.nlm.nih.gov/pubmed/18652671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-55
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