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RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats
AIM: To test the role of the Beclin 1-dependent autophagy pathway in brain damage during cerebral ischemia. METHODS: Focal cerebral ischemia was established in rats using a middle cerebral artery occlusion (MCAO) model. A lentiviral vector-associated RNA interference (RNAi) system was stereotaxicall...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006642/ https://ncbi.nlm.nih.gov/pubmed/19574998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.79 |
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