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Multiparameter flow cytometric analysis of CD4 and CD8 T cell subsets in young and old people

BACKGROUND: T cell-mediated immunity in elderly people is compromised in ways reflected in the composition of the peripheral T cell pool. The advent of polychromatic flow cytometry has made analysis of cell subsets feasible in unprecedented detail. RESULTS: Here we document shifts in subset distribu...

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Autori principali: Koch, Sven, Larbi, Anis, Derhovanessian, Evelyna, Özcelik, Dennis, Naumova, Elissaveta, Pawelec, Graham
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515281/
https://ncbi.nlm.nih.gov/pubmed/18657274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-5-6
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