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Effect of Culture at Low Oxygen Tension on the Expression of Heat Shock Proteins in a Panel of Melanoma Cell Lines

OBJECTIVE: Tumours are commonly hypoxic and this can be associated with aggressive tumour type, metastasis and resistance to therapy. Heat shock proteins (hsps) are induced in response to hypoxia, provide cancer cells with protection against tumour-associated stressors and chaperone oncoproteins tha...

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Autores principales: Shipp, Christopher, Derhovanessian, Evelyna, Pawelec, Graham
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382244/
https://ncbi.nlm.nih.gov/pubmed/22761656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037475
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