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Single-headed mode of kinesin-5

In most organisms, kinesin-5 motors are essential for mitosis and meiosis, where they crosslink and slide apart the antiparallel microtubule half-spindles. Recently, it was shown using single-molecule optical trapping that a truncated, double-headed human kinesin-5 dimer can step processively along...

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Detalles Bibliográficos
Main Authors: Kaseda, Kuniyoshi, Crevel, Isabelle, Hirose, Keiko, Cross, Robert A
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515207/
https://ncbi.nlm.nih.gov/pubmed/18552767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.96
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