Antigen-specific T-T interactions regulate CD4 T-cell expansion

The regulation of CD4 T-cell numbers during an immune response should take account of the amount of antigen (Ag), the initial frequency of Ag-specific T cells, the mix of naive versus experienced cells, and (ideally) the diversity of the repertoire. Here we describe a novel mechanism of T-cell regul...

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Detalhes bibliográficos
Main Authors: Helft, Julie, Jacquet, Alexandra, Joncker, Nathalie T., Grandjean, Isabelle, Dorothée, Guillaume, Kissenpfennig, Adrien, Malissen, Bernard, Matzinger, Polly, Lantz, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515122/
https://ncbi.nlm.nih.gov/pubmed/18539897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-114389
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