A Common Variation in Deiodinase 1 Gene DIO1 Is Associated with the Relative Levels of Free Thyroxine and Triiodothyronine

Introduction: Genetic factors influence circulating thyroid hormone levels, but the common gene variants involved have not been conclusively identified. The genes encoding the iodothyronine deiodinases are good candidates because they alter the balance of thyroid hormones. We aimed to thoroughly exa...

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Autors principals: Panicker, Vijay, Cluett, Christie, Shields, Beverley, Murray, Anna, Parnell, Kirstie S., Perry, John R. B., Weedon, Michael N., Singleton, Andrew, Hernandez, Dena, Evans, Jonathan, Durant, Claire, Ferrucci, Luigi, Melzer, David, Saravanan, Ponnusamy, Visser, Theo J., Ceresini, Graziano, Hattersley, Andrew T., Vaidya, Bijay, Dayan, Colin M., Frayling, Timothy M.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2008
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515080/
https://ncbi.nlm.nih.gov/pubmed/18492748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-0397
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