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A Common Variation in Deiodinase 1 Gene DIO1 Is Associated with the Relative Levels of Free Thyroxine and Triiodothyronine

Introduction: Genetic factors influence circulating thyroid hormone levels, but the common gene variants involved have not been conclusively identified. The genes encoding the iodothyronine deiodinases are good candidates because they alter the balance of thyroid hormones. We aimed to thoroughly exa...

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Detalhes bibliográficos
Main Authors: Panicker, Vijay, Cluett, Christie, Shields, Beverley, Murray, Anna, Parnell, Kirstie S., Perry, John R. B., Weedon, Michael N., Singleton, Andrew, Hernandez, Dena, Evans, Jonathan, Durant, Claire, Ferrucci, Luigi, Melzer, David, Saravanan, Ponnusamy, Visser, Theo J., Ceresini, Graziano, Hattersley, Andrew T., Vaidya, Bijay, Dayan, Colin M., Frayling, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515080/
https://ncbi.nlm.nih.gov/pubmed/18492748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-0397
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