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Targeted gene deletion of heme oxygenase 2 reveals neural role for carbon monoxide

Neuronal nitric oxide synthase (nNOS) generates NO in neurons, and heme-oxygenase-2 (HO-2) synthesizes carbon monoxide (CO). We have evaluated the roles of NO and CO in intestinal neurotransmission using mice with targeted deletions of nNOS or HO-2. Immunohistochemical analysis demonstrated colocali...

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Hlavní autoři: Zakhary, Randa, Poss, Kenneth D., Jaffrey, Samie R., Ferris, Christopher D., Tonegawa, Susumu, Snyder, Solomon H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences of the USA 1997
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC25126/
https://ncbi.nlm.nih.gov/pubmed/9405702
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