High-frequency leader sequence switching during coronavirus defective interfering RNA replication.

A system was developed that exploited defective interfering (DI) RNAs of coronavirus to study the role of free leader RNA in RNA replication. A cDNA copy of mouse hepatitis virus DI RNA was placed downstream of the T7 RNA polymerase promoter to generate DI RNAs capable of extremely efficient replica...

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Publié dans:	J Virol
Auteurs principaux:	Makino, S, Lai, M M
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.12.5285-5292.1989
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