High-frequency leader sequence switching during coronavirus defective interfering RNA replication.
A system was developed that exploited defective interfering (DI) RNAs of coronavirus to study the role of free leader RNA in RNA replication. A cDNA copy of mouse hepatitis virus DI RNA was placed downstream of the T7 RNA polymerase promoter to generate DI RNAs capable of extremely efficient replica...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1989
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.12.5285-5292.1989 |
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