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Construction of a poliovirus type 1/type 2 antigenic hybrid by manipulation of neutralization antigenic site II.

There are three serotypes of poliovirus, poliovirus type 1 (PV-1), PV-2, and PV-3. These viruses each display four distinct neutralization antigenic sites, designated N-AgI, N-AgII, N-AgIIIA, and N-AgIIIB. It has been demonstrated previously that part of N-AgI can be replaced with heterogeneous amin...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Murdin, A D, Wimmer, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251190/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2479772/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.12.5251-5257.1989
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