Temperature-sensitive mutants identify crucial structural regions of simian virus 40 large T antigen.

We have completed the cloning and sequencing of all known temperature-sensitive, amino acid substitution mutants of simian virus 40 large T antigen (tsA mutants). Surprisingly, many of the mutants isolated from distinct viral strains by different laboratories are identical. Thus, 17 independently is...

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Pubblicato in:	J Virol
Autori principali:	Loeber, G, Tevethia, M J, Schwedes, J F, Tegtmeyer, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2778883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.10.4426-4430.1989
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