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Temperature-sensitive mutants identify crucial structural regions of simian virus 40 large T antigen.

We have completed the cloning and sequencing of all known temperature-sensitive, amino acid substitution mutants of simian virus 40 large T antigen (tsA mutants). Surprisingly, many of the mutants isolated from distinct viral strains by different laboratories are identical. Thus, 17 independently is...

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Main Authors: Loeber, G, Tevethia, M J, Schwedes, J F, Tegtmeyer, P
格式: Artigo
語言:Inglês
出版: 1989
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC251062/
https://ncbi.nlm.nih.gov/pubmed/2778883
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