α(+)-Thalassemia protects children against disease caused by other infections as well as malaria

In the South West Pacific region, the striking geographical correlation between the frequency of α(+)-thalassemia and the endemicity of Plasmodium falciparum suggests that this hemoglobinopathy provides a selective advantage against malaria. In Vanuatu, paradoxically, α(+)-thalassemia increases the...

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Главные авторы: Allen, S. J., O’Donnell, A., Alexander, N. D. E., Alpers, M. P., Peto, T. E. A., Clegg, J. B., Weatherall, D. J.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences of the USA 1997
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC25106/
https://ncbi.nlm.nih.gov/pubmed/9405682
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