Molecularly engineered vaccine which expresses an immunodominant T-cell epitope induces cytotoxic T lymphocytes that confer protection from lethal virus infection.

Identification of a single viral T-cell epitope, associated with greater than 95% of the virus-specific cytotoxic T-lymphocyte (CTL) activity in BALB/c (H-2d) mice (J. L. Whitton, A. Tishon, H. Lewicki, J. Gebhard, T. Cook, M. Salvato, E. Joly, and M. B. A. Oldstone, J. Virol. 63:4303-4310, 1989), p...

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Pubblicato in:	J Virol
Autori principali:	Klavinskis, L S, Whitton, J L, Oldstone, M B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2476571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.10.4311-4316.1989
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