Molecularly engineered vaccine which expresses an immunodominant T-cell epitope induces cytotoxic T lymphocytes that confer protection from lethal virus infection.

Documenti analoghi

• Molecular analyses of a five-amino-acid cytotoxic T-lymphocyte (CTL) epitope: an immunodominant region which induces nonreciprocal CTL cross-reactivity.
  di: Whitton, J L, et al.
  Pubblicazione: (1989)
• A recombinant minigene vaccine containing a nonameric cytotoxic-T-lymphocyte epitope confers limited protection against Listeria monocytogenes infection.
  di: An, L L, et al.
  Pubblicazione: (1996)
• Polymorphism of cytotoxic T-lymphocyte clones that recognize a defined nine-amino-acid immunodominant domain of lymphocytic choriomeningitis virus glycoprotein.
  di: Joly, E, et al.
  Pubblicazione: (1989)
• A common antiviral cytotoxic T-lymphocyte epitope for diverse major histocompatibility complex haplotypes: implications for vaccination.
  di: Oldstone, M B, et al.
  Pubblicazione: (1992)
• A "string-of-beads" vaccine, comprising linked minigenes, confers protection from lethal-dose virus challenge.
  di: Whitton, J L, et al.
  Pubblicazione: (1993)