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Single-amino-acid substitution in an antigenic site of influenza virus hemagglutinin can alter the specificity of binding to cell membrane-associated gangliosides.

Antigenic variants of influenza virus A/Mem/1/71-Bel/42 (H3N1) selected with monoclonal antibodies and having single substitutions in their hemagglutinins were examined for their ability to hemagglutinate and hemolyse erythrocytes coated with different gangliosides. The majority of variants, includi...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Suzuki, Y, Kato, H, Naeve, C W, Webster, R G
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251045/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2476569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.10.4298-4302.1989
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