Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression.
A method is described for the production of recombinant adeno-associated virus (AAV) stocks that contain no detectable wild-type helper AAV. The recombinant viruses contained only the terminal 191 nucleotides of the AAV chromosome bracketing a nonviral marker gene. trans-Acting AAV functions were pr...
Gardado en:
| Publicado en: | J Virol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1989
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250975/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2547998/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.9.3822-3828.1989 |
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