Cellular recombination pathways and viral terminal repeat hairpin structures are sufficient for adeno-associated virus integration in vivo and in vitro.

The human parvovirus adeno-associated virus (AAV) is unique in its ability to target viral integration to a specific site on chromosome 19 (ch-19). Recombinant AAV (rAAV) vectors retain the ability to integrate but have apparently lost this ability to target. In this report, we characterize the term...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Yang, C C, Xiao, X, Zhu, X, Ansardi, D C, Epstein, N D, Frey, M R, Matera, A G, Samulski, R J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230226/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.9231-9247.1997
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