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DNA binding and gene regulation by the herpes simplex virus type 1 protein ICP4 and involvement of the TATA element.

We report the results of fine mapping the sequences responsible for negative regulation of immediate-early (IE) gene 3 by its own gene product, ICP4. Affinity-purified ICP4 binds the transcriptional start site of IE gene 3 and protein-protein interactions induce a secondary mobility shift that footp...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: DiDonato, J A, Muller, M T
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250965/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2760982/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.9.3737-3747.1989
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