Isolation of herpes simplex virus regulatory protein ICP4 as a homodimeric complex.

The viral polypeptide ICP4 (or Vmw175) is synthesized during the immediate early phase of infection by herpes simplex virus and regulates the transcription of delayed early and late viral genes. We obtained a partially purified preparation of soluble ICP4 under nondenaturing conditions. Physical con...

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Bibliographic Details
Main Authors: Metzler, D W, Wilcox, K W
Format: Artigo
Language:Inglês
Published: 1985
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC254937/
https://ncbi.nlm.nih.gov/pubmed/2991559
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