Viral protein R of human immunodeficiency virus types 1 and 2 is dispensable for replication and cytopathogenicity in lymphoid cells.

Viral protein R (VPR) is conserved in human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2). To assess its function, we have constructed mutations within the vpr coding regions of HIV-1 and HIV-2 predicted to express truncated VPR products. Infectious virus was produced by each proviral clone...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Dedera, D, Hu, W, Vander Heyden, N, Ratner, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250884/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2524599/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.7.3205-3208.1989
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