Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.

A rearrangement of the c-H-ras locus was detected in a T-cell line (DA-2) established from a Moloney leukemia virus-induced tumor. This rearrangement was associated with the high-level expression of H-ras RNA and the H-ras gene product, p21. DNA from DA-2 cells transformed fibroblasts in DNA transfe...

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Autors principals: Ihle, J N, Smith-White, B, Sisson, B, Parker, D, Blair, D G, Schultz, A, Kozak, C, Lunsford, R D, Askew, D, Weinstein, Y
Format: Artigo
Idioma:Inglês
Publicat: 1989
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC250850/
https://ncbi.nlm.nih.gov/pubmed/2542606
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