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Identification of a novel latency-specific splice donor signal within the herpes simplex virus type 1 2.0-kilobase latency-associated transcript (LAT): translation inhibition of LAT open reading frames by the intron within the 2.0-kilobase LAT.

Herpes simplex virus type 1 establishes latent infection in trigeminal ganglia of mice infected via the eye. A family of three colinear viral transcripts (LATs), 2.0, 1.5, and 1.45 kb, is present in latently infected ganglia. To characterize these LATs, lambda gt10 cDNA libraries were constructed wi...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Spivack, J G, Woods, G M, Fraser, N W
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250769/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1658375/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.12.6800-6810.1991
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