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Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

The production of subtle or conditional mutations in mice through the combined use of site-specific and homologous recombination has become an increasingly widespread experimental paradigm in mammalian genetics. Embryonic stem cells containing recombinase transgenes that were expressed in the male g...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: O’Gorman, Stephen, Dagenais, Nicole A., Qian, Min, Marchuk, Yelena
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405659/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14602
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