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Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

The production of subtle or conditional mutations in mice through the combined use of site-specific and homologous recombination has become an increasingly widespread experimental paradigm in mammalian genetics. Embryonic stem cells containing recombinase transgenes that were expressed in the male g...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: O’Gorman, Stephen, Dagenais, Nicole A., Qian, Min, Marchuk, Yelena
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405659/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14602
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