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Construction and characterization of a herpes simplex virus type 1 mutant unable to transinduce immediate-early gene expression.

A herpes simplex virus mutant, in1814, possessing a 12-base-pair insertion in the gene encoding the transinducing factor Vmw65 has been constructed. The insertion abolished the ability of Vmw65 to transinduce immediate-early (IE) gene expression and to form a protein-DNA complex with cell proteins a...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Ace, C I, McKee, T A, Ryan, J M, Cameron, J M, Preston, C M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250644/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2539517/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.5.2260-2269.1989
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