Construction and characterization of a herpes simplex virus type 1 mutant unable to transinduce immediate-early gene expression.

A herpes simplex virus mutant, in1814, possessing a 12-base-pair insertion in the gene encoding the transinducing factor Vmw65 has been constructed. The insertion abolished the ability of Vmw65 to transinduce immediate-early (IE) gene expression and to form a protein-DNA complex with cell proteins a...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ace, C I, McKee, T A, Ryan, J M, Cameron, J M, Preston, C M
Format: Artigo
Langue:Inglês
Publié: 1989
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC250644/
https://ncbi.nlm.nih.gov/pubmed/2539517
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