The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation.

We investigated the possible translational regulatory roles played by the interferon-induced, double-stranded-RNA-activated protein kinase (P68) and its natural substrate, eucaryotic initiation factor 2 (eIF-2), in poliovirus-infected cells. We demonstrated that protein kinase P68 was both highly au...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Black, T L, Safer, B, Hovanessian, A, Katze, M G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2539516/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.5.2244-2251.1989
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