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The integrity of the stem structure of human immunodeficiency virus type 1 Tat-responsive sequence of RNA is required for interaction with the interferon-induced 68,000-Mr protein kinase.

A number of eucaryotic viruses have devised strategies to minimize the deleterious effects on protein synthesis caused by activation of the interferon-induced, double-stranded-RNA-activated protein kinase, P68. In a recent report, we described the down regulation of the P68 protein kinase in cells i...

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Main Authors: Roy, S, Agy, M, Hovanessian, A G, Sonenberg, N, Katze, M G
格式: Artigo
語言:Inglês
出版: 1991
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC239801/
https://ncbi.nlm.nih.gov/pubmed/1702840
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