Type 1 diabetes risk for HLA-DR3 haplotypes depends on genotypic context: Association of DPB1 and HLA class I loci among DR3 and DR4 matched Italian patients and controls

Patients with high-risk HLA-DR-DQ genotypes for type 1 diabetes (T1D) were compared to HLA-matched controls to evaluate T1D risk for other HLA loci, including HLA-A, -B, -Cw, and DPB1. Patients (n=133) with high-risk genotypes (DR3/DR3, DR3/DR4, DR4/DR4) were selected from the Lazio (Rome) region of...

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Main Authors: Noble, Janelle A., Martin, Adelle, Valdes, Ana M., Lane, Julie A., Galgani, Andrea, Petrone, Antonio, Lorini, Renata, Pozzilli, Paolo, Buzzetti, Raffaella, Erlich, Henry A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2505335/
https://ncbi.nlm.nih.gov/pubmed/18486765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2008.02.003
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