Transglutaminase-catalyzed inactivation of glyceraldehyde 3-phosphate dehydrogenase and α-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length

Several adult-onset neurodegenerative diseases are caused by genes with expanded CAG triplet repeats within their coding regions and extended polyglutamine (Q(n)) domains within the expressed proteins. Generally, in clinically affected individuals n ≥ 40. Glyceraldehyde 3-phosphate dehydrogenase bin...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Cooper, Arthur J. L., Sheu, K.-F. Rex, Burke, James R., Onodera, Osamu, Strittmatter, Warren J., Roses, Allen D., Blass, John P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC25053/
https://ncbi.nlm.nih.gov/pubmed/9356496
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk