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Chagas’ disease parasite-derived neurotrophic factor activates cholinergic gene expression in neuronal PC12 cells
A parasite-derived neurotrophic factor (PDNF) produced by the Chagas’ disease parasite Trypanosoma cruzi binds nerve growth factor (NGF) receptor TrkA, increasing receptor autophosphorylation, activating phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK/Erk) pathways, a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2505116/ https://ncbi.nlm.nih.gov/pubmed/18502403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.03.082 |
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