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Crystal Structure of a Dimerized Cockroach Allergen Bla g 2 Complexed with a Monoclonal Antibody

The crystal structure of a 1:1 complex between the German cockroach allergen Bla g 2 and the Fab′ fragment of a monoclonal antibody 7C11 was solved at 2.8-Å resolution. Bla g 2 binds to the antibody through four loops that include residues 60-70, 83-86, 98-100, and 129-132. Cation-π interactions exi...

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Main Authors: Li, Mi, Gustchina, Alla, Alexandratos, Jerry, Wlodawer, Alexander, Wünschmann, Sabina, Kepley, Christopher L., Chapman, Martin D., Pomés, Anna
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504871/
https://ncbi.nlm.nih.gov/pubmed/18519566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800937200
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