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Light-activated DNA binding in a designed allosteric protein

An understanding of how allostery, the conformational coupling of distant functional sites, arises in highly evolvable systems is of considerable interest in areas ranging from cell biology to protein design and signaling networks. We reasoned that the rigidity and defined geometry of an α-helical d...

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Detalhes bibliográficos
Main Authors: Strickland, Devin, Moffat, Keith, Sosnick, Tobin R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504796/
https://ncbi.nlm.nih.gov/pubmed/18667691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709610105
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