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OXYGEN TENSION REGULATES PREOSTEOCYTE MATURATION AND MINERALIZATION

The goal of this investigation was to test the hypothesis that low pO(2) regulates bone cell mineralization. MLO-A5 and MLO-Y4 cells were cultured in monolayer and alginate scaffolds in hypoxia (2% O(2)) or normoxia (20% O(2)). Reduction of the O(2) tension from 20% to 2% resulted in reduced mineral...

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Bibliografiske detaljer
Main Authors: Zahm, Adam, Bucaro, Michael, Srinivas, Vickram, Shapiro, Irving M., Adams, Christopher S.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504750/
https://ncbi.nlm.nih.gov/pubmed/18485858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2008.03.010
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