Tonic Facilitation of Glutamate Release by Presynaptic NR2B-Containing NMDA Receptors Is Increased in the Entorhinal Cortex of Chronically Epileptic Rats

We have shown previously that when postsynaptic NMDA receptors are blocked, the frequency, but not amplitude, of spontaneous EPSCs (sEPSCs) at synapses in the entorhinal cortex is reduced by NMDA receptor antagonists, demonstrating that glutamate release is tonically facilitated by presynaptic NMDA...

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Detalhes bibliográficos
Main Authors: Yang, Jian, Woodhall, Gavin L., Jones, Roland S. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504723/
https://ncbi.nlm.nih.gov/pubmed/16407536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4413-05.2006
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