Felbamate but not phenytoin or gabapentin reduces glutamate release by blocking presynaptic NMDA receptors in the entorhinal cortex

We have shown that a number of anticonvulsant drugs can reduce glutamate release at synapses in the rat entorhinal cortex (EC) in vitro. We have also shown that presynaptic NMDA receptors (NMDAr) tonically facilitate glutamate release at these synapses. In the present study we determined whether, ph...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Jian, Wetterstrand, Caroline, Jones, Roland S.G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Science Publishers 2007
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496957/
https://ncbi.nlm.nih.gov/pubmed/17980555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2007.09.005
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