Brain-Derived Neurotrophic Factor Transgenic Mice Exhibit Passive Avoidance Deficits, Increased Seizure Severity and In Vitro Hyperexcitability in the Hippocampus and Entorhinal Cortex

Transgenic mice overexpressing brain-derived neurotrophic factor from the β-actin promoter were tested for behavioral, gross anatomical and physiological abnormalities. Brain-derived neurotrophic factor messenger RNA overexpression was widespread throughout brain. Overexpression declined with age, s...

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Huvudupphovsmän: Croll, S. D., Suri, C., Compton, D. L., Simmons, M. V., Yancopoulos, G. D., Lindsay, R. M., Wiegand, S. J., Rudge, J. S., Scharfman, H. E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1999
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504500/
https://ncbi.nlm.nih.gov/pubmed/10501474
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