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Arsenite-induced mitotic death involves stress response and is independent of tubulin polymerization

Arsenite, a known mitotic disruptor, causes cell cycle arrest and cell death at anaphase. The mechanism causing mitotic arrest is highly disputed. We compared arsenite to the spindle poisons nocodazole and paclitaxel. Immunofluorescence analysis of α-tubulin in interphase cells demonstrated that, wh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Taylor, B. Frazier, McNeely, Samuel C., Miller, Heather L., States, J. Christopher
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504415/
https://ncbi.nlm.nih.gov/pubmed/18485433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.02.030
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