Hit selection with false discovery rate control in genome-scale RNAi screens

RNA interference (RNAi) is a modality in which small double-stranded RNA molecules (siRNAs) designed to lead to the degradation of specific mRNAs are introduced into cells or organisms. siRNA libraries have been developed in which siRNAs targeting virtually every gene in the human genome are designe...

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Main Authors: Zhang, Xiaohua Douglas, Kuan, Pei Fen, Ferrer, Marc, Shu, Xiaohua, Liu, Yingxue C., Gates, Adam T., Kunapuli, Priya, Stec, Erica M., Xu, Min, Marine, Shane D., Holder, Daniel J., Strulovici, Berta, Heyse, Joseph F., Espeseth, Amy S.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2008
主題:
Computational Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504311/
https://ncbi.nlm.nih.gov/pubmed/18628291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn435
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