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Dissection of reverse gyrase activities: insight into the evolution of a thermostable molecular machine†

Reverse gyrase is a peculiar DNA topoisomerase, specific of thermophilic microorganisms, which induces positive supercoiling into DNA molecules in an ATP-dependent reaction. It is a modular enzyme and comprises an N-terminal helicase-like module fused to a C-terminal topoisomerase IA-like domain. Th...

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Autors principals: Valenti, Anna, Perugino, Giuseppe, D’Amaro, Anna, Cacace, Andrea, Napoli, Alessandra, Rossi, Mosè, Ciaramella, Maria
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504306/
https://ncbi.nlm.nih.gov/pubmed/18614606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn418
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